The Manhattan Street Fund

The Manhattan Street Fund The Manhattan Street Fund goes hand in hand with the Manhattan Street Capital raising process and le

Tavo Biotherapeutics, a Laguna Beach, California-based developer of novel therapies for glaucoma and retinal disease, ra...
06/07/2026

Tavo Biotherapeutics, a Laguna Beach, California-based developer of novel therapies for glaucoma and retinal disease, raised $17m in funding. The company intends to use the funds to support ongoing clinical and preclinical development activities for its TAV-001 and TAV-002 programs, expand its research capabilities, and progress toward upcoming clinical milestones.

ClearNote Health, a San Diego, CA-based company dedicated to improving early detection for cancer, raised $52M in fundin...
05/31/2026

ClearNote Health, a San Diego, CA-based company dedicated to improving early detection for cancer, raised $52M in funding. The company intends to use the funds to support continued commercial expansion, operational scale-up, clinical study ex*****on, and product development.

Vital Signals, a San Francisco, CA-based health company that supports understanding, tracking, and managing blood pressu...
05/24/2026

Vital Signals, a San Francisco, CA-based health company that supports understanding, tracking, and managing blood pressure and hypertension, raised $15M in funding. The company intends to use the funds to expand operations and its R&D efforts.

Knit Health, a San Francisco, California-based developer of clinical intelligence AI software for healthcare systems, ra...
05/17/2026

Knit Health, a San Francisco, California-based developer of clinical intelligence AI software for healthcare systems, raised $11.6m in funding. The company intends to use the funds to accelerate the development and deployment of its Large Clinical Behavior Model (LCBM) across health systems, optimizing clinical operations and patient care pathways.

LTZ Therapeutics announced the completion of an oversubscribed $38 million financing round to accelerate development of ...
05/10/2026

LTZ Therapeutics announced the completion of an oversubscribed $38 million financing round to accelerate development of its Universal Myeloid Cell Engager immunotherapy platform and pipeline.

Lighthouse Pharmaceuticals, a Novato, CA-based clinical-stage biopharmaceutical company developing therapies for neurode...
05/03/2026

Lighthouse Pharmaceuticals, a Novato, CA-based clinical-stage biopharmaceutical company developing therapies for neurodegenerative and inflammatory diseases, raised $12M in funding. The company intends to use the funds to support the advancement of Lighthouse’s lead program, LHP588, and the continued expansion of its pipeline.

Tortugas Neuroscience, a Framingham, MA-based neurology-focused biotech company developing novel medicines with derisked...
04/26/2026

Tortugas Neuroscience, a Framingham, MA-based neurology-focused biotech company developing novel medicines with derisked mechanisms of action, for large and well-defined indications, raised $106M in financing.

Calyxo, Inc., a Pleasanton, CA-based medical device company, raised $40M in funding. The company intends to use the fund...
04/19/2026

Calyxo, Inc., a Pleasanton, CA-based medical device company, raised $40M in funding. The company intends to use the funds to expand its commercial infrastructure, advance clinical and health economic evidence generation through ongoing and future studies evaluating long-term outcomes and downstream healthcare utilization, and support continued innovation in kidney stone care.

Endovascular Engineering, Inc., a Menlo Park, CA-based commercial-stage medical technology company, raised $80M in fundi...
04/12/2026

Endovascular Engineering, Inc., a Menlo Park, CA-based commercial-stage medical technology company, raised $80M in funding. The company intends to use the funds to support the commercialization of its new Hēlo Thrombectomy Platform for treating pulmonary embolism, the third leading cause of cardiovascular death.

Ambrosia Biosciences, a Boulder, CO-based drug discovery company, raised $100M in funding. The company intends to use th...
04/05/2026

Ambrosia Biosciences, a Boulder, CO-based drug discovery company, raised $100M in funding. The company intends to use the funds to advance its novel oral small-molecule GLP-1 into a Phase 1 clinical trial. Continued development of its other small molecule programs, including GIP and amylin.

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