The Manhattan Street Fund

The Manhattan Street Fund The Manhattan Street Fund goes hand in hand with the Manhattan Street Capital raising process and le

Superluminal Medicines, a Boston, MA-based biotechnology company integrating AI/ML, protein dynamics, and structural bio...
09/06/2026

Superluminal Medicines, a Boston, MA-based biotechnology company integrating AI/ML, protein dynamics, and structural biology to generate G protein-coupled receptor (GPCR) targets, raised $60M in financing. The company intends to use the funds to support advancing its lead program for rare genetic forms of obesity and hypothalamic obesity, advance additional pipeline programs, and further expand its portfolio of new small-molecule GPCR-targeted therapies for endocrine and cardiometabolic diseases.

Onos Health, a San Francisco, CA-based behavioral health clinical intelligence platform for health plans, raised $17M in...
08/30/2026

Onos Health, a San Francisco, CA-based behavioral health clinical intelligence platform for health plans, raised $17M in funding. The company intends to use the funds to further expand its proprietary AI platform and scale commercial deployments with national and regional health plans.

Astromech, a Dallas, TX-based computational biology and predictive artificial intelligence startup spun out from de-exti...
08/23/2026

Astromech, a Dallas, TX-based computational biology and predictive artificial intelligence startup spun out from de-extinction company Colossal Biosciences, raised $20m in funding. The company will use the capital to expand its specialized machine learning and computational biology research teams, acquire new multi-species genomic datasets, and build out the heavy computing infrastructure required to scale its foundational AI models.

Khartis Therapeutics, a San Diego, CA-based provider of a biotechnology platform developing therapies for immunological ...
08/16/2026

Khartis Therapeutics, a San Diego, CA-based provider of a biotechnology platform developing therapies for immunological and chronic diseases, raised $50M in funding. The company intends to use the funds to support the advancement of its lead program, an oral selective IGF-1R inhibitor designed for the treatment of thyroid eye disease (TED), as well as the continued development of its broader pipeline of oral small molecule medicines targeting clinically validated immunology pathways.

LifeMine Therapeutics Inc., a Watertown, MA-based clinical-stage biopharmaceutical company leveraging digital genomics r...
08/09/2026

LifeMine Therapeutics Inc., a Watertown, MA-based clinical-stage biopharmaceutical company leveraging digital genomics research technology, has raised $263M in funding. The company intends to use the funds to accelerate the clinical development of its lead program, LIFE-001, including a planned Phase 2 kidney transplant study and Phase 1b islet cell transplant study, and advance its pipeline of new transplantation and immunology therapies.

Healia, a Columbus, OH-based provider of a healthcare benefits platform for dual-income families and employers, raised $...
08/02/2026

Healia, a Columbus, OH-based provider of a healthcare benefits platform for dual-income families and employers, raised $14M in funding. The company intends to use the funds to expand operations and its development efforts.

Crystalys Therapeutics, a San Diego, CA-based clinical-stage biopharmaceutical company, raised $130M in funding. The com...
07/26/2026

Crystalys Therapeutics, a San Diego, CA-based clinical-stage biopharmaceutical company, raised $130M in funding. The company intends to use the funds to support late-stage global clinical development and commercialization preparation of dotinurad, a new once-daily oral URAT1 inhibitor.

410 Medical, Inc., a Durham, NC-based medical device company developing technology solutions for emergency and critical ...
07/19/2026

410 Medical, Inc., a Durham, NC-based medical device company developing technology solutions for emergency and critical care, raised $12M in funding. The company intends to use the funds to scale its commercial operations and support the launch of LifeFlow’s infuser.

Pearl Health, a NYC-based healthcare technology company helping manage risk and deliver better care to Medicare patients...
07/12/2026

Pearl Health, a NYC-based healthcare technology company helping manage risk and deliver better care to Medicare patients, raised $110M in funding. The company intends to use the funds to expand its AI platform, turning clinical intelligence into measurable outcomes, and accelerate its growth across enterprise health system and payer partnerships, its expansion into Medicare Advantage, and new risk offerings.

Vanna Health, a San Francisco, California-based developer of a value-based health technology platform for serious mental...
07/05/2026

Vanna Health, a San Francisco, California-based developer of a value-based health technology platform for serious mental illness (SMI) care, raised $17m in funding. The company intends to use the funds to accelerate its clinical and operational reach into new regional markets, expand its internal healthcare coordination workforce, and deepen its community-centered technology infrastructure.

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